Table of Contents
International Journal of Proteomics
Volume 2011 (2011), Article ID 145010, 8 pages
http://dx.doi.org/10.1155/2011/145010
Research Article

Comprehensive Proteomic Profiling of Aldehyde Dehydrogenases in Lung Adenocarcinoma Cell Lines

1Molecular Diagnostics Program, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M5-C800, Seattle, WA 98109, USA
2University of Michigan Comprehensive Cancer Center, 8D17 300 NIB, University of Michigan, Ann Arbor, MI 48109, USA
3Department of Surgery, University of Michigan, 1150 West Medical Center Drive, Room A510A MSRB-1, Ann Arbor, MI 48109, USA

Received 1 July 2011; Accepted 14 August 2011

Academic Editor: Tadashi Kondo

Copyright © 2011 Qing Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. K. Rekha, L. Sreerama, and N. E. Sladek, “Intrinsic cellular resistance to oxazaphosphorines exhibited by a human colon carcinoma cell line expressing relatively large amounts of a class-3 aldehyde dehydrogenase,” Biochemical Pharmacology, vol. 48, no. 10, pp. 1943–1952, 1994. View at Publisher · View at Google Scholar · View at Scopus
  2. N. Tsukamoto, J. Chen, and A. Yoshida, “Enhanced expressions of glucose-6-phosphate dehydrogenase and cytosolic aldehyde dehydrogenase and elevation of reduced glutathione level in cyclophosphamide-resistant human leukemia cells,” Blood Cells, Molecules and Diseases, vol. 24, no. 2, pp. 231–238, 1998. View at Publisher · View at Google Scholar · View at Scopus
  3. J. S. Moreb, “Aldehyde dehydrogenase as a marker for stem cells,” Current Stem Cell Research & Therapy, vol. 3, no. 4, pp. 237–246, 2008. View at Google Scholar · View at Scopus
  4. C. Chen, Y. Wei, M. Hummel et al., “Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma,” PLoS One, vol. 6, no. 1, Article ID e16466, 2011. View at Publisher · View at Google Scholar
  5. J. Li and B. P. Zhou, “Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters,” BMC Cancer, vol. 11, p. 49, 2011. View at Publisher · View at Google Scholar
  6. Y. Chen, D. J. Orlicky, A. Matsumoto, S. Singh, D. C. Thompson, and V. Vasiliou, “Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer,” Biochemical and Biophysical Research Communications, vol. 405, no. 2, pp. 173–179, 2011. View at Publisher · View at Google Scholar
  7. C. van den Hoogen, G. van der Horst, H. Cheung et al., “The aldehyde dehydrogenaseenzyme 7A1 is functionally involved in prostate cancer bone metastasis,” Clinical and Experimental Metastasis. In press.
  8. K. S. Park, S. Y. Cho, H. Kim, and Y. K. Paik, “Proteomic alterations of the variants of human aldehyde dehydrogenase isozymes correlate with hepatocellular carcinoma,” International Journal of Cancer, vol. 97, no. 2, pp. 261–265, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Liang and Y. Shi, “Aldehyde dehydrogenase-1 is a specific marker for stem cells in human lungadenocarcinoma,” Medical Oncology. In press.
  10. J. P. Sullivan, M. Spinola, M. Dodge et al., “Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling,” Cancer Research, vol. 70, no. 23, pp. 9937–9948, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. J. Feng, Q. Qi, A. Khanna et al., “Aldehyde dehydrogenase 1 is a tumor stem cell-Associated marker in lung cancer,” Molecular Cancer Research, vol. 7, no. 3, pp. 330–338, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. J. S. Moreb, H. V. Baker, L. J. Chang et al., “ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells,” Molecular Cancer, vol. 7, article 87, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. S. A. Marchitti, D. J. Orlicky, C. Brocker, and V. Vasiliou, “Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues,” Journal of Histochemistry and Cytochemistry, vol. 58, no. 9, pp. 765–783, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. S. E. Ong and M. Mann, “A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC),” Nature Protocols, vol. 1, no. 6, pp. 2650–2660, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. V. Faca, S. J. Pitteri, L. Newcomb et al., “Contribution of protein fractionation to depth of analysis of the serum and plasma proteomes,” Journal of Proteome Research, vol. 6, no. 9, pp. 3558–3565, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. A. Rauch, M. Bellew, J. Eng et al., “Computational proteomics analysis system (CPAS): an extensible, open-source analytic system for evaluating and publishing proteomic data and high throughput biological experiments,” Journal of Proteome Research, vol. 5, no. 1, pp. 112–121, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. A. Keller, A. I. Nesvizhskii, E. Kolker, and R. Aebersold, “Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search,” Analytical Chemistry, vol. 74, no. 20, pp. 5383–5392, 2002. View at Publisher · View at Google Scholar · View at Scopus
  18. A. I. Nesvizhskii, A. Keller, E. Kolker, and R. Aebersold, “A statistical model for identifying proteins by tandem mass spectrometry,” Analytical Chemistry, vol. 75, no. 17, pp. 4646–4658, 2003. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Choi and A. I. Nesvizhskii, “False discovery rates and related statistical concepts in mass spectrometry-based proteomics,” Journal of Proteome Research, vol. 7, no. 1, pp. 47–50, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. H. Liu, R. G. Sadygov, and J. R. Yates III, “A model for random sampling and estimation of relative protein abundance in shotgun proteomics,” Analytical Chemistry, vol. 76, no. 14, pp. 4193–4201, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. F. M. Brichory, D. E. Misek, A. M. Yim et al., “An immune response manifested by the common occurrence of annexins I and II autoantibodies and high circulating levels of IL-6 in lung cancer,” Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 17, pp. 9824–9829, 2001. View at Publisher · View at Google Scholar · View at Scopus
  22. Z. A. Rasheed, J. Yang, Q. Wang et al., “Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma,” Journal of the National Cancer Institute, vol. 102, no. 5, pp. 340–351, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. C. Visus, D. Ito, A. Amoscato et al., “Identification of human aldehyde dehydrogenase 1 family member a1 as a novel CD8+ T-cell-defined tumor antigen in squamous cell carcinoma of the head and neck,” Cancer Research, vol. 67, no. 21, pp. 10538–10545, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. T. Nakanishi, T. Takeuchi, K. Ueda, H. Murao, and A. Shimizu, “Detection of eight antibodies in cancer patients' sera against proteins derived from the adenocarcinoma A549 cell line using proteomics-based analysis,” Journal of Chromatography B, vol. 838, no. 1, pp. 15–20, 2006. View at Publisher · View at Google Scholar