Proteomic Characterization of Cerebrospinal Fluid from Ataxia-Telangiectasia (A-T) Patients Using a LC/MS-Based Label-Free Protein Quantification Technology
Figure 3
MRM analysis of A-T biomarker candidates. Relative protein expression levels were determined by averaging the area-under-the-Curve (AUC) for each selected MRM transition for each peptide shown in Table 4. For secretogranin-2 and IGFBP7, the fold-changes from both MRM peptides were also averaged. Statistical analysis was performed by ANOVA models using PROC MIXED in SAS. .