Synthesis and Characterization of Chemically Cross-Linked Acrylic Acid/Gelatin Hydrogels: Effect of pH and Composition on Swelling and Drug Release

Table 7

Effect of degree of cross-linking on drug release kinetics of AA/Gelatin hydrogels in solutions of different pH values.

Sample codes	EGDMA contents (%)	pH	Zero-order kinetics		First-order kinetics		Higuchi model
			(h^−1)		(h^−1)		(h^−1)
U7	0.65	1.2	2.052	0.984	0.025	0.987	0.0833	0.976
		5.5	4.853	0.996	0.077	0.984	0.195	0.971
		7.5	6.247	0.981	0.134	0.988	0.083	0.976
U8	0.75	1.2	1.423	0.980	0.016	0.984	0.057	0.973
		5.5	4.176	0.990	0.062	0.995	0.169	0.983
		7.5	5.121	0.989	0.097	0.966	0.211	0.993
U9	0.85	1.2	1.412	0.977	0.016	0.983	0.058	0.993
		5.5	4.019	0.997	0.056	0.994	0.160	0.963
		7.5	5.251	0.992	0.090	0.989	0.212	0.978