Sulfated Alkyl Glucopyranans with Potent Antiviral Activity Synthesized by Ring-Opening Copolymerization of Anhydroglucose and Alkyl Anhydroglucose Monomers

Figure 5

SPR binding affinity of (a) sulfated (16)-α-D-glucopyranan with 3-O-octadecyl groups in the proportion of 2.8 mol% and with and (b) dextran sulfate with to poly-L-lysine, respectively. The apparent kinetic constants were  1/Ms,  1/s, and  M for sulfated 3-O-octadecyl (16)-α-D-glucopyranan (a) and  1/Ms,  1/s, and  M for standard dextran sulfate.

(a)

(b)