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International Journal of Polymer Science
Volume 2015 (2015), Article ID 782653, 11 pages
Review Article

Polymers for Cardiovascular Stent Coatings

1Ernst-Moritz-Arndt University, Clinic for Internal Medicine B, Ferdinand-Sauerbruch-Straße, 17475 Greifswald, Germany
2DZHK (German Centre for Cardiovascular Research), Fleischmannstrasse 42-44, 17489 Greifswald, Germany

Received 23 December 2014; Revised 20 April 2015; Accepted 20 April 2015

Academic Editor: Crispin Dass

Copyright © 2015 Anne Strohbach and Raila Busch. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Polymers have found widespread applications in cardiology, in particular in coronary vascular intervention as stent platforms (scaffolds) and coating matrices for drug-eluting stents. Apart from permanent polymers, current research is focussing on biodegradable polymers. Since they degrade once their function is fulfilled, their use might contribute to the reduction of adverse events like in-stent restenosis, late stent-thrombosis, and hypersensitivity reactions. After reviewing current literature concerning polymers used for cardiovascular applications, this review deals with parameters of tissue and blood cell functions which should be considered to evaluate biocompatibility of stent polymers in order to enhance physiological appropriate properties. The properties of the substrate on which vascular cells are placed can have a large impact on cell morphology, differentiation, motility, and fate. Finally, methods to assess these parameters under physiological conditions will be summarized.