Thermal Synthesis of Polypeptides from N-Butyloxycarbonyl Oligopeptides Containing Aspartyl Residue at C-Terminus

Figure 1

Preparation of N-t-butyloxycarbonyl-amino acid and peptide active esters. Boc₂O: di-tert-butyl dicarbonate; NEt₃: triethylamine; HONSu: N-hydroxysuccinimide; DCC: N,N′-dicylohexylcarbodiimide.