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International Journal of Polymer Science
Volume 2017, Article ID 9761047, 8 pages
https://doi.org/10.1155/2017/9761047
Research Article

Chitosan Associated with the Extract of Unripe Banana Peel for Potential Wound Dressing Application

1Institute of Science and Technology, Federal University of Alfenas, Rod. José A. Vilela 11.999, 37715-400 Poços de Caldas, MG, Brazil
2Institute of Chemistry, São Paulo State University “Júlio de Mesquita Filho”, Rua Prof. Francisco Degni 55, 14800-060 Araraquara, SP, Brazil
3Center of Agricultural Sciences, Federal University of São Carlos, Rod. Anhanguera Km 174, Araras, SP, Brazil

Correspondence should be addressed to Patrícia Bataglini Franco; moc.liamtoh@inilgattabtap

Received 19 April 2017; Accepted 29 May 2017; Published 3 July 2017

Academic Editor: Hossein Roghani-Mamaqani

Copyright © 2017 Patrícia Bataglini Franco et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The authors report the preparation of chitosan membranes associated with the extract of unripe banana peel. Extracts were prepared by decoction, using boiling distilled water. The extraction process was repeated three times. First and third extracts served as solvent to prepare chitosan membranes by solvent evaporation technique. The chitosan membranes associated with the first and third extracts of unripe banana peel exhibit good flexibility, transparency, and uniformity. Scanning Electron Microscopy images showed dense membranes. Brownish color of membranes was observed due to the presence of tannins, which was confirmed by Infrared Spectroscopy analysis. Thermal properties of the membranes were evaluated by Differential Scanning Calorimetry (DSC), which exhibited good thermal stability at physiological temperature (37°C). At this temperature and pH 7.2, membranes were also able to absorb fluids. The hydrophilic character of the membranes was determined by contact angle measurements. The membranes demonstrated their capacity for gaseous exchange and exhibited water-vapor permeability (WVP) rates comparable to injured skin one. Finally, high number of viable dermal fibroblasts was observed by indirect cytotoxicity assay suggesting potential application of these membranes as skin wound dressing.