Research Article

Ibuprofen Release from Poly(ethyl cyanoacrylate) Nanoparticles Prepared by Semicontinuous Heterophase Polymerization

Table 1

Average particle size and IB content of the nanoparticles.

PolymerizationECA (g)TW80 (g)pH (°C)Loading efficiency (%)Dz1 (nm)

F1/5/110.161526.4 ± 1.458.1 ± 2.3
F1/5/1.510.161.5528.5 ± 1.355.3 ± 1.7
F.5/15/150.50.0811517.6 ± 1.242.9 ± 1.8
F.5/15/1.50.50.081.51526.4 ± 1.231.2 ± 2.1
F.5/15/1.750.50.081.751530.8 ± 0.710.3 ± 1.5

by QLS.