International Journal of Polymer Science / 2018 / Article / Tab 1

Review Article

Analytical Methods to Characterize and Purify Polymeric Nanoparticles

Table 1

Analytical chromatographic techniques.

TechniqueCharacteristics that analysesAdvantagesDisadvantagesReferences

Gel permeation chromatography (GPC)Molecular weightRapid and simpleInteraction sample with column fillingWilliams [10]
High resolutionNeverova and Van Eyk [8]
Cho et al. [1]

High-performance liquid chromatography (HPLC)Quantification of activesHigh resolutionInteraction sample with column fillingNeverova and Van Eyk [8]
PurificationRapid and easy performanceSapsford et al. [9]
Low cost/sample
Small sample volumes

Size exclusion chromatography (SEC)Molecular weightHigh resolutionInteraction sample with column fillingKostanski et al. [25]
Rapid and simpleNeed of a labelling tagSapsford et al. [9]
Rebolj et al. [26]

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