Research Article
Mechanism of MCP-1 in Acute Lung Injury and Advanced Therapy by Drug-Loaded Dextrin Nanoparticle
Table 1
Effects of LPS and LPS/CCR2 antagonist interventions on PaO
2, PaO
2/FiO
2, and wet/dry weight ratio in LPS-induce ALI rat models (
, ).
| | Group | PaO2 (mmHg) | PaO2/FiO2 (mmHg) | Wet/dry weight ratio |
| | NC group | 104.30 ± 7.36 | 458.70 ± 12.05 | 4.05 ± 0.15 | | L group | 61.50 ± 7.18# | 261.30 ± 7.07# | 6.02 ± 0.44# | | R + L group | 83.30 ± 3.83 | 331.30 ± 9.87 | 5.02 ± 0.33 | | DNPR + L group | 95.78 ± 4.51# | 379.85 ± 8.19# | 4.47 ± 0.43# | | value | 114.07 | 1027.386 | 90.662 | | value | 0.000 | 0.000 | 0.000 |
|
|
Compared with NC group ( ); #: compared with R + L group ( ). |
