Research Article
Study on the Role of the Inclusion Complexes with 2-Hydroxypropyl-β-cyclodextrin for Oral Administration of Amiodarone
Table 10
Pharmacokinetic parameters of pure AMD suspension and F and Fc0 formulations in Wistar rats following single-dose oral administration (, ).
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: peak plasma concentration; : time to reach peak plasma concentration; : area under curve from 0 h to last determined experimental data; : area under the plasma concentration time curve from time zero to infinity; : elimination rate constant; : elimination half-life; : systemic relative bioavailability. aWith reference to pure AMD suspension; bwith reference to formulation F1. vs. AMD. |