Research Article
Highly Porous pH-Responsive Carboxymethyl Chitosan-Grafted-Poly (Acrylic Acid) Based Smart Hydrogels for 5-Fluorouracil Controlled Delivery and Colon Targeting
Table 2
Amount of 5-FU loaded and released from selected samples.
| Sample codes | Amount of 5-FU loaded (g/g of dry gel) | Amount of 5-FU released (%) (pH of the solution) | By swelling | By weight | By extraction | 1.2 | 6.5 | 7.5 |
| HS1 | 0.065 | 0.069 | 0.060 | 27.76 | 61.79 | 79.13 | HS2 | 0.071 | 0.073 | 0.069 | 23.65 | 69.90 | 82.56 | HS3 | 0.072 | 0.077 | 0.074 | 24.99 | 70.25 | 83.19 | HS7 | 0.082 | 0.083 | 0.078 | 26.49 | 77.69 | 88.89 | HS8 | 0.076 | 0.078 | 0.072 | 24.21 | 70.74 | 83.93 | HS9 | 0.059 | 0.063 | 0.061 | 21.37 | 66.14 | 77.08 |
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