Research Article

Highly Porous pH-Responsive Carboxymethyl Chitosan-Grafted-Poly (Acrylic Acid) Based Smart Hydrogels for 5-Fluorouracil Controlled Delivery and Colon Targeting

Table 2

Amount of 5-FU loaded and released from selected samples.

Sample codesAmount of 5-FU loaded (g/g of dry gel)Amount of 5-FU released (%) (pH of the solution)
By swellingBy weightBy extraction1.26.57.5

HS10.0650.0690.06027.7661.7979.13
HS20.0710.0730.06923.6569.9082.56
HS30.0720.0770.07424.9970.2583.19
HS70.0820.0830.07826.4977.6988.89
HS80.0760.0780.07224.2170.7483.93
HS90.0590.0630.06121.3766.1477.08