Review Article

Progress on Preparation of pH/Temperature-Sensitive Intelligent Hydrogels and Applications in Target Transport and Controlled Release of Drugs

Table 1

Critical solution temperature of temperature-sensitive intelligent hydrogel.

NameCritical solution temperature/°CReferences

Poly N-piperidine5.5[54]
BMA-PNIPAM10[42]
Poly N-methyl-N-PNIPAM22.3[54]
Acrylamide-L-proline methylase24[54]
Poly N-PNIPAM30.9[54]
Poly-N,N-diethyl acrylamide32[37]
Chitosan/β-sodium glycerophosphate/gelatin hydrogels32.6[55]
Chitosan/gelatin/genipin/β-sodium glycerophosphate hydrogel37[3]
Polyvinyl methyl ether38.0[54]
PEO-PLLA-PEG polymer hydrogel45[41]
Poly N-ethyl methacrylamide50.0[54]
Poly N-ethyl acrylamide72.0[54]
N-TBA/M,N-dimethylacrylamide copolymer20-80[56]
Methacrylic acid 2-(2-methoxy ethoxy) ethyl ester (MEO2MA)-methacrylic acid oligosity (glycol)ester (OEGMA) copolymer hydrogel26-90[57]