Silymarin and Vanillic Acid Silver Nanoparticles Alleviate the Carbon Tetrachloride-Induced Nephrotoxicity in Male Rats
Table 1
Effect of treating CCl4-induced nephrotoxicity in male rats vanillic acid, vanillic acid AgNPs, and silymarin on kidney function indices.
Parameters (mg/dl)
Statistics
G1 (negative control)
G2 (positive control)
G3 (treated with vanillic acid)
G4 (treated with vanillic acid AgNPs)
G5 (treated with silymarin)
Urea
Mean ± SE
e
a
b
c
d
LSD 0.05 = 3.878
T-test
—
−25.10***
07.95***
07.82***
11.77***
Creatinine
Mean ± SE
e
a
b
c
d
LSD 0.05 = 0.091
T-test
—
−28.61***
10.87***
11.750***
18.46***
Uric acid
Mean ± SE
e
a
b
c
d
LSD 0.05 = 0.229
T-test
—
−45.45***
11.86***
25.75***
23.91***
-test values ***: significant at . ANOVA analysis: means with different superscripts (a, b, c, d, or e) are significantly different at . LSD: least significant difference.
