Clinical Study

Baseline Comorbidities in a Population-Based Cohort of Rheumatoid Arthritis Patients Receiving Biological Therapy: Data from the Australian Rheumatology Association Database

Table 2

Baseline demographic and disease characteristics of the ARAD RA cohort (n = 624)*.

Mean (SD)

Age (years)57.0 (12.5)
Duration of RA (symptoms), years16.0 (11.0)
Duration of RA (since diagnosis), years14.4 (10.2)
ESR (mm/hr)35.8 (26.8)
CRP (mg/L)33.7 (38.2)
PBS tender/swollen joint count# 23 (12)
Overall pain due to arthritis in last week (0–100)44.0 (25.8)
Overall patient global impression of disease activity in the last week (0–100)42.0 (25.3)
Mean (SD) HAQ score (0–3, 0 no = disability) 1.8 (0.72)
Mean (SD) AQoL score (0-1, 1 = full health) 0.42 (0.24)
SF-36 score (0–100, 100 = perfect health)
Physical component28.05 (9.88)
Mental component43.66 (12.57)
EuroQoL (UK weights) (0-1, 1 = perfect health) 0.46 (0.32)

N (%)

Female449 (72)
Smoking history
Current101 (16.2)
Past266 (42.6)
Never257 (41.2)

Alcohol consumption
Never178 (28.9)
Sometimes373 (60.7)
Every day64 (10.4)

At least one concomitant DMARDs572 (91.7)
Methotrexate (oral or IM)375 (60.1)
Salazopyrin73 (11.7)
Leflunomide166 (26.6)
Hydroxychloroquine115 (18.4)
Cyclosporin16 (2.6)
Azathioprine9 (1.4)
Gold8 (1.3)
Penicillamine4 (0.6)

Currently taking prednisolone or prednisone420 (67.3)

slightly different for some variables.#Pharmaceutical Benefits Scheme (PBS) definition (see Table 1).