Treatment of Complicated Henoch-Schönlein Purpura with Mycophenolate Mofetil: A Retrospective Case Series Report
Table 3
Treatment protocols and outcomes of patients.
Corticostroid Dose/Route/Duration
Response to corticostroid
Mycophenolate mofetil (MMF) Dose/Duration
Response to Mycophenolate mofetil (MMF)
Mean arterial pressure (mmHg) before treatment by Mycophenolate mofetil (MMF)
Mean arterial pressure (mmHg) one week after treatment by Mycophenolate mofetil (MMF)
Case 1
Prednisolone 2 mg/kg/d PO for 8 weeks
Stroid dependency
30 mg/kg For 3 weeks
Significant recovery in 48 hours
84
86
Case 2
Prednisolone 2 mg/kg/d PO for 8 weeks
Stroid dependency
30 mg/kg For 6 weeks
Significant recovery in one week
78
77
Case 3
Prednisolone 2 mg/kg/d PO for 8 weeks
Stroid dependency
30 mg/kg For 8 weeks
Significant recovery in one month
80
80
Case 4
Prednisolone 2 mg/kg/d PO for 2 weeks
No response
30 mg/kg For 8 weeks
Significant recovery in one month
86
85
Case 5
Methyl prednisolone 20 mg/kg IV for 3 doses every other day then Prednisolone 2 mg/kg/d for first 4 weeks and 2 mg/kg/every other day for second 4weeks
No response
30 mg/kg For 6 month
Significant recovery of proteinuria but continuation of microscopic hematuria
86
90
Case 6
Prednisolone 2 mg/kg/d PO for first 4 weeks and 2 mg/kg/every other day for second 4weeks