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International Journal of Rheumatology
Volume 2010 (2010), Article ID 312159, 3 pages
Case Report

The Enigma of Vasculitis

1Department of Medicine (Rheumatology and Nephrology & Hypertension), Danbury Hospital, Danbury, CT 06810, Valhalla, NY 10595, USA
2New York Medical College, Valhalla, NY 10595, USA

Received 28 January 2010; Revised 5 April 2010; Accepted 9 April 2010

Academic Editor: Bernhard Manger

Copyright © 2010 Daniela Ghetie et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We describe the case of an 86-year-old man presenting with clinical symptoms suggestive of Temporal Arteritis. The evolution of the case prompted extensive work-up, including temporal artery and kidney biopsy. Based on the clinical and pathological findings, a diagnosis of ANCA-negative granulomatous necrotizing vasculitis involving the small-, medium-, and large-size vessels was made. The patient was treated with prednisone and cyclophosphamide, which was later switched to rituximab. The patient remained asymptomatic under this regimen and stabilization of his kidney function was achieved.