Serum Endoglin Levels in Patients Suffering from Systemic Sclerosis and Elevated Systolic Pulmonary Arterial Pressure
Table 1
SSc patients’ clinical characteristics.
Clinical characteristics
SSc- sPAP patients
SSc-non sPAP patients
Age (in years)
.4
Age at onset
.78
Male : female
2.3 : 1
2.3 : 1
1
Duration (means SD), years
.19
lSSc
13
13
1
dSSc
7
7
1
sPAP mmHg at rest
.0001
Raynaud%
100
100
1
Time of onset of Raynaud
.81
Rodnan score
.21
Calcinosis%
45
15
.041
Telangiectasias%
100
100
1
Renal crisis%
0
0
Ischemic cutaneous ulcers%
0
0
Gastrointestinal involvement%
60
80
.15
normal HRCTT%
60
100
NS
HRCTT PAH%
40
0
NS
Anticentromere ab%
75
60
.21
Anti-Scl-70 ab%
10
20
NS
ANA%
15
20
NS
Methotrexate
11
11
1
Cyclophosphamide
6
7
.73
SD: standard deviation, lSSc: limited systemic sclerosis, dSSc: diffuse systemic sclerosis, sPAP: systolic pulmonary arterial pressure, HRCTT: high-resolution computed tomography of thorax, PAH: pulmonary arterial hypertension. Fisher's or Wilcoxon test was used for calculating the differences between groups.
