Low-Dose Naltrexone for Pruritus in Systemic Sclerosis
Figure 1
Biopsy specimens from patient 1: H&E-stained section shows moderate perivascular and periadnexal inflammation and thickening of dermal collagen (20X). There are several mast cells in perivascular, interstitial, and periadnexal distribution with granular-appearing cytoplasm (IHC mast cell tryptase 20X).