Anti-𝜶-enolase Antibodies in Serum from Pediatric Patients Affected by Inflammatory Diseases: Diagnostic and Pathogenetic Insights

Table 2

AAE IgA and AAE IgG in healthy controls and patients. Levels and percentage of positivity of anti-𝛼-enolase IgA and IgG in healthy controls (HCs) and patients with juvenile idiopathic arthritis (JIA), celiac disease (CD), Crohn’s disease (ChD), hereditary periodic fevers (HPF), and PFAPA syndrome (PFAPA) were reported as mean and standard deviation (SD). AAE levels are expressed as arbitrary units per mL (AU/mL) and AAE positivity as number and percentage of sera with titre above the cut-off. Patients’ AAE levels are compared to healthy control by t-test and P values are reported.

	AAE IgA	AAE IgA+	P	AAE IgG	AAE IgG+	P
HC (n = 80)	15.44±5.21	0		16.79±5.81	0
JIA (n = 31)	31.21±22.11	16 (52%)	4.4exp−4	42.52±13.28	27 (87%)	3.4exp−12
CD (n = 55)	25.72±24.74	18 (33%)	0.004	34.23±12.42	36 (65%)	1.3exp−14
CrD (n = 59)	29.60±16.69	31 (53%)	2.8exp−8	43.04±18.39	44 (75%)	6.7exp−16
HPF (n = 20)	37.41±34.51	13 (65%)	0.01	46.57±21.21	16 (80%)	8.4exp−6
PFAPA (n = 29)	11.59±7.87	1 (4%)	0.02	14.09±6.46	1 (4%)	0.05