Clinical Study
Is IgG4-Related Disease a Cause of Xerostomia? A Cohort Study of 60 Patients
Table 1
Clinical, histopathological, and therapeutic data.
| | Group | A | B | C | D |
| | SS criteria | Yes | Yes | No | No | | Positive immunostaining with anti IgG4 antibodies | No | Yes | Yes | No | No. of patients
(total ) | 22 | 5 | 13 | 20 | | Age | 57 ± 13 | 66 ± 10 | 58 ± 7 | 66 ± 14 | | Sex ratio (M : F) | 1 : 4.5 | 1 : 4 | 1 : 5.5 | 1 : 4 | | Atopic background | 8 | 1 | 2 | 7 | | Salivary glands swellings | 0 | 0 | 3 | 1 | | Extra-salivary involvements | 11 | 4 | 6 | 7 | | Focus score ≥ 1 | 20 | 5 | 6 | 3 | | IgG4+ immunostaining on LSGB | 0 | 4 | 13 | 0 | | Fibrosis | 13 | 3 | 7 | 7 | | Corticotherapy | 3 | 2 | 7 | 8 | | Response to steroids | 1 | 0 | 4 | 6 |
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