Immunosuppression Adversely Affects TST but Not IGRAs in Patients with Psoriasis or Inflammatory Musculoskeletal Diseases

Table 1

Patient characteristics.

Variable	Total; (𝑛=109)	Group*; (𝑛=21)	Group 2^†; (𝑛=74)	Group 3^‡; (𝑛=14)
Age, mean years	57.5	51	58.7	60.9
Quartiles 25–75%	48.5–68.4	41.4–57.4	48.5–70.3	50.8–66
Sex
Female, 𝑛 (%)	65 (60)	8 (38)	49 (66)	8 (57)
Born in TB-endemic country^§
Yes, 𝑛 (%)	12 (11)	0 (0)	9 (12)	3 (21)
Contact with TB
Yes, 𝑛 (%)	12 (11)	0 (0)	11 (15)	3 (21)
Previous TB-history
No, 𝑛 (%)	97 (89)	19 (90)	64 (86)	14 (100)
Full treatment, n(%)	4 (4)	1 (5)	3 (4)	0 (0)
Partially treated, 𝑛 (%)	8 (7)	1 (5)	7 (9)	0 (0)
Positive chest X-ray^||
Yes, 𝑛 (%)	8 (7)	0 (0)	7 (9)	1 (7)
BCG vaccination
Yes, 𝑛 (%)	46 (42)	16 (76)	27 (36)	3 (21)
Treatment
Corticosteroids, 𝑛 (%)	38 (35)	1 (5)	31 (42)	6 (43)
Cytostatics, 𝑛 (%)	48 (44)	9 (43)	35 (47)	4 (29)
Biological, 𝑛 (%)	6 (6)	4 (19)	2 (3)	0 (0)

*Psoriasis.
^†Inflammatory musculoskeletal diseases: rheumatoid arthritis 38, ankylosing spondylitis 11, vasculitis 7, seronegative polyarthritis 6, oligoarthritis 4, myositis 3, juvenile idiopathic arthritis 2, chronic reactive arthritis 1, systemic lupus erythematosus 1, spondyloarthritis 1.
^‡Miscellaneous inflammatory conditions: bronchial asthma 2, diabetes/renal transplantation 1, chronic alcholism 1, hypersedimentation 1, lung infection (mycobacterium avium-intracellulare) 1, Poncet’s disease 1, Polycystic disease/renal transplantation 1, renal dysfunction 1, tubulointerstitial nephritis 1, pleuritis, lung fibrosis 1, lymphoma 1, universal arteriosclerosis 1, spinal pseudotumor 1.
^§Cambodia, Chile, Cuba, Estonia (𝑛=2), Morocco (𝑛=2), Poland, Somalia (𝑛=2), Turkey, Ukraine.
^||Available in 99 patients.