Clinical Study

Immunosuppression Adversely Affects TST but Not IGRAs in Patients with Psoriasis or Inflammatory Musculoskeletal Diseases

Table 4

The univariate analysis of the TB risk factors with a positive outcome of the B-TbIFNg test.

VariableAll patients
B-TbINFγ
Odds ratioSignificance
Positive (21.1)(95% CI) <

Age, mean (test neg. mean)57.558.7 (58.8)1.0 (0.96–1.04)1
Sex, female, (%)65 (59.6)7 (46.7)0.6 (0.2–1.8)0.4
BCG vaccination, (%)46 (42.2)4 (26.7)0.4 (0.1–1.5)0.2

Born in TB-endemic country, (%)12 (11.0)3 (20.0)2.6 (0.5–12.2)0.3
Contact with TB, (%)15 (13.8)4 (26.7)3.0 (0.7–12.6)0.2
Previous TB-history, (%)12 (11.0)4 (26.7)3.7 (0.9–16.1)0.08
Any risk factor for LTBI, (%)33 (30.3)9 (60.0)5.0 (1.5–16.6)0.009

Positive chest X-ray, (%)8 (7.3)1 (7.1)0.9 (0.1–9.0)0.9

Group 1, (%)21 (19.3)2 (10.5)0.4 (0.07–1.7)0.2
Group 2, (%)71 (65.1)11 (24.4)1.3 (0.7–2.5)0.4
Group 3, (%)17 (15.6)2 (28.6)1.2 (0.6–2.1)0.6

Corticosteroids, (%)38 (34.9)3 (20.0)0.5 (0.1–2.1)0.4
Cytostatic treatment, (%)48 (44.0)6 (40.0)1.0 (0.3–3.3)1.0
Biological treatment, (%)6 (5.5)0 (0)1.0