Clinical Study
Immunosuppression Adversely Affects TST but Not IGRAs in Patients with Psoriasis or Inflammatory Musculoskeletal Diseases
Table 6
The agreement between IGRAs and TST with negative/negative as the reference category.
| | | Negative | Positive | | Concordance | Kappa (std. Error) |
| | | Ly-TbSpot | | | |
| B-TbIFNg | Negative, (%) | 41 (64) | 8 (13) | 64 | 0.88 | 0.71 (0.09) | | Positive, (%) | 0 (0) | 15 (23) | | | | | | | Any risk factor 3.6 (1.06–12) | | | |
| TST cut-off 10 mm | Negative, (%) | 28 (38) | 5(7) | 74 | 0.65 | 0.32 (0.10) | | | | Age 1.14 (1.01–1.29) | | | | | Positive, (%) | 21 (28) | 20 (27) | | | | | | Age 0.94 (0.90–0.98) | | | | | | | Woman 0.22 (0.057–0.87) | Woman 0.071 (0.017–0.30) | | | | | | BCG 3.6 (1.11–12) | | | | |
| | | B-TbIFNγ | | | |
| TST cut off 10 mm | Negative, (%) | 19 (37) | 3 (6) | 51 | 0.61 | 0.26 (0.11) | | Positive, (%) | 17 (33) | 12 (24) | | | | | | Age 0.90 (0.85–0.97) | Age 0.93 (0.87–0.99) | | | | | | Woman 0.17 (0.035–0.78) | Woman 0.13 (0.025–0.72) | | | | | | BCG 4.7 (1.18–18) | | | | | | | Costeroids 0.15 (0.03–0.83) Corticosteroids 0.10 (0.01–0.94) | | | |
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