Clinical Study

Immunosuppression Adversely Affects TST but Not IGRAs in Patients with Psoriasis or Inflammatory Musculoskeletal Diseases

Table 6

The agreement between IGRAs and TST with negative/negative as the reference category.

NegativePositive ConcordanceKappa (std. Error)

Ly-TbSpot

B-TbIFNgNegative, (%)41 (64)8 (13)640.880.71 (0.09)
Positive, (%)0 (0)15 (23)
Any risk factor 3.6 (1.06–12)

TST cut-off 10 mmNegative, (%)28 (38)5(7)740.650.32 (0.10)
Age 1.14 (1.01–1.29)
Positive, (%)21 (28)20 (27)
Age 0.94 (0.90–0.98)
Woman 0.22 (0.057–0.87)Woman 0.071 (0.017–0.30)
BCG 3.6 (1.11–12)

B-TbIFNγ

TST cut off 10 mmNegative, (%)19 (37)3 (6)510.610.26 (0.11)
Positive, (%)17 (33)12 (24)
Age 0.90 (0.85–0.97)Age 0.93 (0.87–0.99)
Woman 0.17 (0.035–0.78)Woman 0.13 (0.025–0.72)
BCG 4.7 (1.18–18)
Costeroids 0.15 (0.03–0.83) Corticosteroids 0.10 (0.01–0.94)