International Journal of Rheumatology / 2013 / Article / Tab 3

Clinical Study

Capability and Limitations of Recent Diagnostic Criteria for Autoimmune Pancreatitis

Table 3

International consensus diagnostic criteria for type 1 AIP [11].

(1) (P) Pancreatic enlargement
 Level 1: typical imaging, diffuse
 Level 2: indeterminate imaging, segmental/focal
(2) (D) Narrowing of the main pancreatic duct on ERP
 Level 1: >1/3 length or multiple stricture
 Level 2: segmental/focal
(3) (S) Serum IgG4 level
 Level 1: >270 mg/dL
 Level 2: 135–270 mg/dL
(4) (OOI) Other organ involvement
 Level 1: histology (≥3 criteria), or sclerosing cholangitis, or  retroperitoneal fibrosis
 Level 2: histology (2 criteria), or salivary/lacrimal gland  swelling, or renal involvement
(5) (H) Histology of the pancreas (LPSP)
 Level 1: ≥3 of 4 criterions (periductal lymphoplasmacytic  infiltrate without granulocytic infiltration, obliterative  phlebitis, storiform fibrosis, and abundant IgG4-positive  cells)
 Level 2: 2 criteria
(6) (Rt) Response to steroid

Definite type 1 diagnosis
 Level 1 histology
 Typical imaging: any non-D level 1/level 2
 Indeterminate imaging: two or more from level 1 + level 2 D
level 1 S/OOI + Rt or level 1 D + level 2 S/OOI/H + Rt
Probable type 1 diagnosis
 Indeterminate imaging: level 2 S/OOI/H + Rt
AIP-NOS
 D1/2 + Rt

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