The Relationship between Mechanical Hyperalgesia Assessed by Manual Tender Point Examination and Disease Severity in Patients with Chronic Widespread Pain: A Cross-Sectional Study
Table 6
Variables classified according to the ICF model. Differences between groups at a tender point threshold level at 8 with the pain response cutoff set at 2 at the tender point examination.
Outcome variable
TPC: 0–8
TPC: 9–18
value
Mean (SD)
Range
Mean (SD)
Range
Body
Muscle strength UE (PTQ extension)
96.8 (30.6)
38–160
83.0 (37.5)
7–199
0.04
Muscle strength UE (PTQ flexion)
46.6 (17.9)
18–85
39.2 (18.3)
5–84
0.026
Grip strength, max.
192.5 (63.61)
76–304
172.2 (84.6)
8–408
0.176
Vitality (SF-36)
26.3 (16.9)
0–70
21.2 (17.2)
0–75
0.105
Fatigue (FIQ)
7.3 (2.2)
1.3–10
8.1 (1.9)
1.4–10
0.014
Rest (FIQ)
6.5 (2.5)
0.6–10
7.7 (2.3)
0.1–10
0.005
Well-being (SF-36)
55.2 (20.4)
20–92
55.7 (20.7)
0–100
0.904
Well-being (FIQ)
6.6 (2.6)
0–10
7.5 (2.7)
0–10
0.079
Anxiety (FIQ)
3.9 (3.6)
0–10
4.5 (3.4)
0–10
0.328
Anxiety (GAD-10)
17.3 (9.4)
3–42
19.5 (9.8)
1–50
0.217
Depression (FIQ)
4.3 (3.4)
0–10
3.7 (3.4)
0–10
0.348
Depression (MDI)
21.1 (10.7)
5–45
21.7 (10.7)
3–50
0.763
Bodily pain (SF-36)
29.1 (12.3)
0–60
22.3 (15.3)
0–84
0.034
Pain intensity (FIQ)
6.4 (1.9)
1.5–9.5
7.2 (1.9)
0–10
0.021
Muscle stiffness (FIQ)
4.8 (2.9)
0–9.8
6.5 (2.7)
0–10
0.001
Tiredness mobility (Mob-T)
2.4 (1.8)
0–6
1.5 (1.6)
0–6
0.009
Pain detection threshold (PDT)
15.0 (8.4)
4.2–46.2
11.7 (7.2)
0.7–42.5
0.02
Pain tolerance threshold (PTT)
37.1 (14.2)
12.3–72.8
30.7 (14.6)
9.2–86.7
0.019
Activity and participation
ADL ability motor (AMPS)
1.29 (0.49)
0.11–2.45
1.04 (0.49)
0.04–2.82
0.004
ADL ability process (AMPS)
1.16 (0.37)
0.53–1.86
1.08 (0.34)
0.12–2.18
0.204
Walking speed (6-MW)
487.5 (127.3)
142–672
443.8 (111.4)
95–712
0.035
Activity limitations (FIQ)
4.2 (2.3)
0–8.7
5.4 (2.2)
0–9
0.003
Physical functioning (SF-36)
50.8 (19.3)
10–85
41.7 (19.9)
0–95
0.012
Role physical (SF 36)
8.6 (20.14)
0–75
9.9 (21.2)
0–100
0.733
Role emotional (SF-36)
41.2 (41.9)
0–100
45.7 (43.6)
0–100
0.57
Social functioning (SF-36)
52.1 (27.0)
12.5–100
47.4 (26.4)
0–100
0.326
Days of sick leave pr. week (FIQ)
0.89 (1.3)
0–2.9
1.2 (1.7)
0–5.7
0.685
Work ability (FIQ)
5.7 (2.8)
1.4–8.2
6.8 (2.5)
0–10
0.218
Personal
Catastrophizing (CSQ)
15.3 (8.3)
0–33
16.0 (8.4)
0–36
0.628
Perceived control over pain (CSQ)
2.6 (1.4)
0–5
2.4 (1.4)
0–6
0.354
Ability to decrease pain (CSQ)
2.5 (1.4)
0–5
2.3 (1.2)
0–6
0.284
Global measures
FIQ total
54.4 (18.59)
14.8–92.1
62.3 (18.4)
2.9–97.4
0.018
SF-36 PCS
29.7 (7.0)
15.8–43.8
26.5 (6.6)
8.8–50.7
0.01
SF-36 MCS
40.1 (12.6)
20.4–64.3
40.8 (11.9)
14.9–66.6
0.773
General health (SF-36)
34.1 (15.6)
5–77
31.2 (18.5)
0–97
0.4
GAD-10: generalized anxiety disorder; MDI: major depression inventory; SF-36: short-form-36 health survey; FIQ: fibromyalgia impact questionnaire; SF-36 PCS: SF-36 physical composite score; PTQ: peak torque; SF-36 MCS: SF-36 mental composite score; CSQ: coping strategy questionnaire; AMPS: assessment of motor and process skills; Mob-T: mobility tiredness; 6-MW: 6-minute walk.