Research Article

Risk of Type 2 Diabetes among Osteoarthritis Patients in a Prospective Longitudinal Study

Table 2

Age-sex specific incidence rate per 1000 person years, relative risks (RRs), and the 95% confidence intervals (CIs) of diabetes mellitus (DM).

VariablesMen Women
Age < 65 years
( = 9,086)
Age ≥ 65 years
( = 6,040)
Age < 65 years
( = 11,184)
Age ≥ 65 years
( = 11,868)

DM incidence rate (1,000)12.5 (11.9–13.1)13.0 (12.1–13.9)10.2 (9.7–10.8)10.4 (9.9–11.0)

ExposureRR (95% CI)RR (95% CI)RR (95% CI)RR (95% CI)
OA unadjusted1.32 (1.19–1.46)0.99 (0.86–1.14)1.53 (1.38–1.70)1.32 (1.19–1.48)
OA adjusted1.16 (1.04–1.28)0.94 (0.82–1.09)1.27 (1.15–1.41)1.21 (1.08–1.35)
SES
 1 (low)1.40 (1.19–1.66)1.18 (0.95–1.46)1.57 (1.33–1.85)1.16 (0.98–1.39)
 21.27 (1.08–1.50)1.18 (0.94–1.47)1.53 (1.30–1.80)1.17 (0.98–1.40)
 31.42 (1.20–1.67)0.91 (0.72–1.16)1.35 (1.14–1.61)1.18 (0.98–1.43)
 41.07 (0.90–1.27)1.09 (0.86–1.37)1.12 (0.94–1.34)1.15 (0.95–1.39)
 5 (high)ReferenceReferenceReferenceReference
Obesity1.95 (1.70–2.24)1.62 (1.25–2.11)1.73 (1.54–1.95)1.98 (1.69–2.32)
COPD1.22 (1.06–1.41)1.01 (0.84–1.20)1.20 (1.05–1.36)1.13 (0.99–1.29)
Hypertension2.14 (1.92–2.38)1.43 (1.24–1.65)2.20 (1.99–2.44)1.45 (1.30–1.63)
Hyperlipidemia1.33 (1.16–1.53)1.31 (1.07–1.60)1.18 (1.02–1.36)1.33 (1.14–1.55)
Charlson score1.01 (0.96–1.06)0.99 (0.95–1.03)1.02 (0.97–1.07)0.96 (0.93–1.00)

COPD: chronic obstructive pulmonary disease; SES: socioeconomic status; OA: osteoarthritis.