Clinical and Autoimmune Profile of Scleroderma Patients from Western India

Table 4

Demographic and serological similarities/differences in Indian scleroderma patients in various regions across the country.

Regions of India
	Western; *Present, reference [15]	Northern; Reference [10–12]	Southern; Reference [13, 14]
Disease onset
dsSSc	40.9%	94%, 88.1%
IcSSc	29.1%	6%, 11.9%
Cutaneous
Skin thickening	98.2%
Peripheral vascular
Raynaud’s phenomenon	68.2%, 83.3%	92.9%, 60%	17.3%, 28.2%
Digital ulcers and/or gangrene	20.9%
Pulmonary
Interstitial lung disease (ILD)	88.2%
Pulmonary hypertension	61.2%
Renal	10.9%, 8.3%	3.4%, 6%, 20%	10.3%
Musculoskeletal	39.1%, 54.2%	36.7%, 80%	66.7%
Gastrointestinal	7.3%, 50%
Cardiovascular	13.6%, 12.5%
Autoantibodies
ANA	85.5%	89.1%, 70%
Anti-Scl70	62.7%	55.5%
Anti-centromere	22.7%

There are no published reports from Eastern part of the country.