Familial Mediterranean Fever in Iran: A Report from FMF Registration Center

Table 3

Genotype and phenotype correlations.

	Common combined mutations	The most common alleles
Abdominal pain	V726A-M694V; (12.5%)	M694V; (19.6%)
Fever	V726A-M680I; (13.9%)	M694V; (19.4%)
Chest pain	V726A-M694V and R761H-M694V; (16.7%)	M694V; (29.2%)
Joint pain	M694V-M694V; (33.3%)	M694V; (50%)
Patients with positive family history	V726A-M694V; (26.3%)	M694V; (32.9%)
Age at FMF onset 1 to 10 years	M694V-M694V; (7.1%)	M694V; (18.1%)
Age at FMF onset 10 to 20 years	V726A-M694V; (12.2%)	M694V; (23.2%)
Age at FMF onset after 20 years	V726A-M694V; (23.8%)	M694V; (29.8%)
Male	V726A-M694V; (12.7%)	M694V; (18.3%)
Female	M694V-M694V; (10.4%)	M694V; (24.5%)