The Reliability of a Novel Automated System for ANA Immunofluorescence Analysis in Daily Clinical Practice

Table 3

Visual versus automated detected patterns of antinuclear antibodies by indirect immunofluorescence. Crosstabulation of antinuclear antibodies (ANA) titres by indirect immunofluorescence (IIF) for 89 serum samples that revealed a positive result by visual interpretation of the ANA-IIF-assay 2; concordant results are shown in bold.

Visual interpretation (gold standard)	Automated interpretation, n
	Negative	Homogeneous	Fine speckled	Coarse speckled	Nucleolar	Centromeric	Mitochondrial	Total
Homogeneous	1	18						19
Fine speckled	7	11	1	13		3	1	36
Coarse speckled	4	1		13	1	1		20
Nucleolar	4			3	1	1		9
Centromeric	1			1		1		3
Mitochondrial							1	1
Nuclear dots	1							1
Total	18	30	1	30	2	6	2	89