The Impact of Different Classification Criteria Sets on the Estimated Prevalence and Associated Risk Factors of Diastolic Dysfunction in Rheumatoid Arthritis
Table 5
Independent relationships of 1 SD increase in traditional risk factors and RA disease characteristics with diastolic dysfunction based on new and previous criteria in RA patients with isolated diastolic dysfunction (EF ≥ 50%).
Diastolic dysfunction by new criteria
Diastolic dysfunction by previous criteria
Without LVMI in model
With LVMI in model
Without LVMI in model
With LVMI in model
Odds ratio (95% CI)
Odds ratio (95% CI)
Odds ratio (95% CI)
Odds ratio (95% CI)
Age at disease onset
2.45 (1.20–5.02)
0.01
3.04 (1.36–6.81)
0.01
1.35 (0.83–2.20)
0.23
1.47 (0.88–2.45)
0.14
Sex
3.55 (0.74–17.02)
0.11
3.37 (0.70–16.23)
0.13
1.25 (0.37–1.24)
0.72
1.11 (0.32–3.83)
0.87
Race
1.08 (0.71–1.67)
0.71
1.09 (0.71–1.69)
0.70
1.07 (0.77–1.49)
0.69
1.05 (0.76–1.47)
0.76
Heart rate
0.97 (0.59–1.59)
0.90
0.94 (0.57–1.55)
0.82
1.02 (0.67–1.53)
0.94
0.96 (0.63–1.46)
0.84
Diastolic blood pressure
0.72 (0.43–1.20)
0.20
0.71 (0.42–1.20)
0.21
0.59 (0.40–0.89)
0.01
0.60 (0.40–0.91)
0.01
Waist-hip ratio
1.76 (0.94–3.30)
0.07
1.99 (1.04–3.80)
0.03
1.20 (0.73–1.97)
0.48
1.28 (0.77–2.14)
0.34
Disease duration
1.78 (0.93–3.39)
0.08
1.99 (1.01–3.93)
0.05
1.51 (0.95–2.41)
0.08
1.58 (0.98–2.55)
0.06
Azathioprine
0.63 (0.06–6.33)
0.70
0.57 (0.06–5.75)
0.64
0.49 (0.10–2.56)
0.40
0.45 (0.09–2.34)
0.34
Triglycerides
0.99 (0.81–1.22)
0.94
0.99 (0.81–1.23)
0.38
1.05 (0.92–1.20)
0.43
1.06 (0.92–1.21)
0.43
LVMI
—
0.65 (0.35–1.24)
0.19
—
0.73 (0.46–1.15)
0.18
EF, ejection fraction; LVMI, left ventricular mass indexed to body surface area.