Isolated Ro52 Antibodies as Immunological Marker of a Mild Phenotype of Undifferentiated Connective Tissue Diseases

Table 1

Clinical and serological markers that predict the evolution to each definite connective tissue disease (CTD).

Disease	Predictive evolution factors
	Clinical	Serological
Systemic Lupus Erythematosus (SLE)	Serositis; Alopecia; Photosensitivity; Discoid rash	Anti-dsDNA; Anti-Sm; Antiphospholipid
Sjögren Syndrome (SS)	Raynaud; Xerostomia	Anti-Ro; Anti-La
Systemic Sclerosis (Scl)	Raynaud; Sclerodactyly; Esophageal dysfunction	ANA nucleolar pattern
Rheumatoid Arthritis (RA)	Polyarthritis	Rheumatoid factor