Evaluation of Vitamin D Status in Rheumatoid Arthritis and Its Association with Disease Activity across 15 Countries: “The COMORA Study”
Table 1
Demographic and disease characteristics of rheumatoid arthritis patients.
Characteristics
Age (years)
57.9 ± 12.8 18–88]
Female sex
1172 (82.9)
High educational level
(≥secondary)
950 (67.2)
BMI (kg/m2)
26.3 ± 5 15–53.1]
Current/past smoking
214 (15.1)
Disease duration (years)
8.3 (3.6–15.2)
DAS 28
3.5 ± 1.4 0–8.2]
Disease activity
High
231 (16.3)
Moderate
576 (40.8)
Low
208 (14.7)
Remission
398 (28.2)
Vitamin D level
27.3 ± 15.1 0.1–151]
HAQ
1 ± 0.6 0.4–1]
Glucocortocoid therapy intake
691 (48.9)
Current dose of glucocortocoid (mg/day)
0 0–5]
DMARDs
Immunosuppressor
17 (1.2)
APS
238 (16.8)
Salazopyrin
70 (4.9)
Golds
57 (4)
Methotrexate
763 (54)
Biotherapy
173 (12.2)
Comorbidities
Hypertension
494 (35)
Diabetes
133 (9.4)
Cancer
42 (3)
Lung diseases
110 (7.8)
Renal diseases
40 (2.8)
Anemia and blood diseases
165 (11.8)
Hepatitis B
39 (2.8)
Hepatitis C
18 (1.3)
Liver diseases
51 (3.6)
Ulcer and stomach diseases
166 (11.8)
Mean ± DS; number and percentage; median; BMI: body mass index; DAS28: Disease Activity Score using 28 joints; HAQ: health assessment questionnaire; APS: antimalarial drug, DMARDs: Disease-Modifying Antirheumatic Drugs.