Effects of the Cathepsin K Inhibitor ONO-5334 and Concomitant Use of ONO-5334 with Methotrexate on Collagen-Induced Arthritis in Cynomolgus Monkeys

<div>Relation between joint swelling score at peak and X-ray score at day 63 for (a) individual animals and (b) treatment groups in collagen-induced arthritis monkeys. Data are expressed as mean ± SE; control (n=8), ONO-5334 (n=9), methotrexate (n=8), and combination (n=9).</div>

International Journal of Rheumatology

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Figure 4: Effects of the Cathepsin K Inhibitor ONO-5334 and Concomitant Use of ONO-5334 with Methotrexate on Collagen-Induced Arthritis in Cynomolgus Monkeys 

Figure 4 | Effects of the Cathepsin K Inhibitor ONO-5334 and Concomitant Use of ONO-5334 with Methotrexate on Collagen-Induced Arthritis in Cynomolgus Monkeys 