Clinical Study

Efficacy of Vitamin E in Methotrexate-Induced Hepatotoxicity in Rheumatoid Arthritis: An Open-Label Case-Control Study

Table 3

Comparison of change in transaminase levels from baseline to 3 months of follow-up in between two groups.

Treatment groupControl group value

SGPT (baseline)<0.001
Δ SGPT (median: 29.0) (median: 23.0)0.007
SGOT (baseline)<0.001
Δ SGOT (median: 18.5) (median: 11.0)<0.001

Independent -test. Δ = baseline to 3 months of follow-up. SGPT: serum glutamic pyruvic transaminase; SGOT: serum glutamic-oxaloacetic transaminase.