Review Article

Effect of Polymorphisms in the FCN1, FCN2, and FCN3 Genes on the Susceptibility to Develop Rheumatoid Arthritis: A Systematic Review

Table 1

Data from studies included in the systematic review.

AuthorYearGeneGenetic variantsGeographic regionStudy typeSource of controlsNOSNumber of casesNumber of controls

Pieczarka et al. [11]2015FCN1
FCN2
rs2989727
rs1071583
rs17514136
rs3124954
rs7851696
BrazilCases and controlsCommunity9184264

Addobbati et al. [12]2020FCN1
FCN3
rs2989727
rs10120023
rs17039495
rs10117466
rs10858293
rs532781899
rs28362807
rs4494157
BrazilCases and controlsCommunity9148160

Vander Cruyssen et al. [13]2007FCN1
FCN2
FCN3
rs2989727
rs1071583
rs7865453
ss32469537
ss32469544
rs7851696
rs3813800
BelgiumCases and controlsCommunity9338595

The variants are described according to their RS code (RefSNP) assigned in dbSNP (genetic variant database of the US National Institutes of Health). Available at https://www.ncbi.nlm.nih.gov/snp/. Score on the Newcastle-Ottawa scale (NOS).