Effect of Polymorphisms in the FCN1, FCN2, and FCN3 Genes on the Susceptibility to Develop Rheumatoid Arthritis: A Systematic Review
Table 2
Risk of bias assessment of included studies based on the Newcastle-Ottawa scale.
Study
Newcastle-Ottawa scale domains
Selection
Comparability
Exposition
Total
First author
Year
Proper case definition
Representivity of the cases
Selection of controls
Definition of controls
Control of important factors
Exposure assessment
Same method for the measurement of all subjects
Nonresponse rate
Addobbati C
2015
1
1
1
1
2
1
1
1
9
Pieczarka C
2020
1
1
1
1
2
1
1
1
9
Vander Cruyssen B
2007
1
1
1
1
2
1
1
1
9
A score greater than or equal to 7 indicates low risk of bias and good methodological quality of the case-control study in the domains of selection, comparability, and exposure.