Polymorphism in STAT4 Increase the Risk of Systemic Lupus Erythematosus: An Updated Meta-Analysis

Table 1

Characteristics of individual studies included in meta-analysis.

First author	Time	Ethnicity	Number		T allele (%)		Association
			SLE	Control	SLE	Control	OR	95% CI
Keisuke Kadota	2013	Japanese	75	190	47.3	33.4	1.790	1.218-2.631
Ping Li	2011	Chinese	748	750	41.0	32.2	1.484	1.278-1.723
V Gupta	2018	Indian	394	583	32.9	26.2	1.382	1.134-1.685
Salmaninejad A	2017	Iranian	50	281	39.0	31.9	1.368	0.882-2.123
Mirkazemi S	2013	Iranian	280	281	41.3	31.9	1.502	1.176-1.918
Shu Kobayashi	2008	Japanese	238	752	44.0	31.0	1.744	1.411-2.154
		Japanese	188	940	39.0	31.0	1.432	1.139-1.800
		Japanese	165	212	44.0	30.0	1.833	1.357-2.476
Chikako Kiyohara	2009	Japanese	152	427	37.5	29.0	1.466	1.113-1.931
J. Dang	2014	Chinese	370	576	40.1	30.9	1.543	1.271-1.872
Skonieczna K	2017	Polish	35	50	32.9	21.0	1.841	0.921-3.681
Hwa Chia Chai	2014	Malay	93	110	44.1	32.7	1.621	1.082-2.427
		Chinese	245	294	46.3	37.8	1.423	1.115-1.815
		Indian	22	26	31.8	42.3	0.636	0.275-1.474
Aya Kawasaki	2008	Japanese	308	306	46.3	33.5	1.709	1.357-2.153
Morales RJ P	2008	Colombian	144	410	42.7	31.5	1.624	1.232-2.140
SU Yin	2010	Chinese	252	497	40.3	29.5	1.614	1.289-2.019
WU Xi-mei	2018	Chinese	163	102	50.3	35.3	1.568	1.012-2.431
Bai Suyun	2010	Chinese	102	125	47.1	35.2	1.636	1.121-2.388
Min W	2017	Chinese	1387	2259	40.3	33.2	1.356	1.229-1.495
Miu Qian	2009	Chinese	767	956	42.8	35.8	1.338	1.166-1.536
W Yang,	2009	Chinese	910	1440	46.1	33.4	1.705	1.512-1.923
		Thailand	278	383	48.7	35.2	1.747	1.398-2.183
Taylor KE	2008	American	1398	2560	31.1	22.5	1.556	1.403-1.726
Remmers EF	2007	Swedish	575	416	31.0	22.0	1.597	1.299-1.962
		Swedish	349	416	31.0	23.0	1.504	1.198-1.889
		Swedish	115	416	29.0	22.0	1.458	1.050-2.024
A-K Abelson	2009	Germany	247	220	26.5	21.0	1.365	1.007-1.851
		Italy	221	207	39.4	19.3	2.711	1.989-3.695
		Spain	390	620	32.7	22.1	1.712	1.401-2.094
		Argentina	171	171	41.5	31.9	1.518	1.110-2.076
		Mexico	552	633	54.7	36.4	2.109	1.789-2.487
Total			11384	17609	39.4	29.5	1.579	1.497-1.665

CI: confidence interval; OR: odds ratio.