International Journal of Rheumatology

IgG4-Related Disease


Publishing date
01 Jun 2012
Status
Published
Submission deadline
01 Dec 2011

Lead Editor

1Rheumatology Clinical Research Unit, Massachusetts General Hospital, 55 Fruit Street/Yawkey 2C, Boston, MA 01776, USA

2Department of Pathology, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong

3Department of Gastroenterology and Hepatology, Kansai Medical University, Osaka, Japan

4Division of Hematology and Immunology, Department of Internal Medicine, Kanazawa Medical University, Ishikawa 920-0293, Japan

5Histopathology Section, Institute of Liver Studies, King's College Hospital, Denmark Hill, London SE5 9RS, UK

6Applied Physics, California Institute of Technology, Mail Stop 128-95, Pasadena, CA 91125, USA


IgG4-Related Disease

Description

IgG4-related disease (IgG4-RD) is a rapidly emerging, multiorgan system condition now known to affect multiple organ systems: the pancreas, salivary glands, orbital tissues, aorta, lungs, kidneys, thyroid gland, and others. Patients with this condition have consistent histopathological and immunopathological features across all affected organs. The disease is responsive to glucocorticoids, but such treatment fails to cure the disease in substantial percentages of patients that may vary according to clinical epidemiology and the specific organ system(s) involved. B-cell depletion is a promising approach to treatment, but the full impact of this therapy and its precise mechanisms are unclear. The fundamental basis of IgG4-RD remains obscure, and the full extent of its organ involvement has yet to be defined. Very little is known about the epidemiology of this condition, but the growing medical literature suggests that it may be much more common than generally appreciated.

An international symposium on IgG4-RD will be held in Boston, Mass (USA) from October 4–7, 2011. Manuscripts derived from this symposium will be submitted for peer review and consideration for publication in the International Journal of Rheumatology, an open-access journal. In addition, we invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the clinical features, pathology, radiologic characteristics, pathophysiologic aspects, approaches to treatment of IgG4-RD, and the evaluation of outcomes. We are particularly interested in articles describing basic studies pertaining to the biology of IgG4, mechanistic studies that provide insight into the pathophysiology of IgG4-RD, and new approaches to therapy. Potential topics include, but are not limited to:

  • The morphology of IgG4-RD within discrete organs
  • Pathophysiology and immunological aspects
  • Classification and diagnostic criteria
  • The epidemiology of IgG4-RD and its individual organ system manifestations
  • The natural history of IgG4-RD and response to treatment
  • New treatment approaches
  • Utility of IgG4 concentrations and autoantibodies as biomarkers
  • Manifestations of IgG4-RD in unusual sites
  • The radiology of IgG4-RD
  • Lymphadenopathy and IgG4-RD
  • The risk of malignancy in IgG4-RD

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2013
  • - Article ID 532612
  • - Editorial

IgG4-Related Disease

John H. Stone | John K. C. Chan | ... | Yoh Zen
  • Special Issue
  • - Volume 2012
  • - Article ID 602809
  • - Clinical Study

Pathologies Associated with Serum IgG4 Elevation

Mikael Ebbo | Aurélie Grados | ... | Nicolas Schleinitz
  • Special Issue
  • - Volume 2012
  • - Article ID 358371
  • - Research Article

Prevalence of IgG4-Related Disease in Japan Based on Nationwide Survey in 2009

Kazushige Uchida | Atsushi Masamune | ... | Kazuichi Okazaki
  • Special Issue
  • - Volume 2012
  • - Article ID 609795
  • - Clinical Study

Immunohistochemical Characteristics of IgG4-Related Tubulointerstitial Nephritis: Detailed Analysis of 20 Japanese Cases

Mitsuhiro Kawano | Ichiro Mizushima | ... | Takako Saeki
  • Special Issue
  • - Volume 2012
  • - Article ID 940831
  • - Review Article

Autoantibodies in Autoimmune Pancreatitis

Daniel S. Smyk | Eirini I. Rigopoulou | ... | Dimitrios P. Bogdanos
  • Special Issue
  • - Volume 2012
  • - Article ID 572539
  • - Review Article

IgG4-Related Lymphadenopathy

Yasuharu Sato | Tadashi Yoshino
  • Special Issue
  • - Volume 2012
  • - Article ID 789164
  • - Review Article

IgG4-Related Fibrotic Diseases from an Immunological Perspective: Regulators out of Control?

Laura C. Lighaam | Rob C. Aalberse | Theo Rispens
  • Special Issue
  • - Volume 2012
  • - Article ID 357071
  • - Review Article

Are Classification Criteria for IgG4-RD Now Possible? The Concept of IgG4-Related Disease and Proposal of Comprehensive Diagnostic Criteria in Japan

Kazuichi Okazaki | Hisanori Umehara
  • Special Issue
  • - Volume 2012
  • - Article ID 232960
  • - Clinical Study

Spectrum of Disorders Associated with Elevated Serum IgG4 Levels Encountered in Clinical Practice

Jay H. Ryu | Ryohei Horie | ... | Eunhee S. Yi
  • Special Issue
  • - Volume 2012
  • - Article ID 207056
  • - Research Article

Histopathologic Overlap between Fibrosing Mediastinitis and IgG4-Related Disease

Tobias Peikert | Bijayee Shrestha | ... | Eunhee S. Yi
International Journal of Rheumatology
 Journal metrics
Acceptance rate16%
Submission to final decision50 days
Acceptance to publication25 days
CiteScore3.100
Impact Factor-
 Submit