International Journal of Rheumatology

Systemic Sclerosis 2011


Publishing date
01 Nov 2011
Status
Published
Submission deadline
01 May 2011

Lead Editor

1Division of Immunology and Rheumatology, Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA 94305, USA

2Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland

3Division of Rheumatology, Georgetown University, Washington, DC, USA

4Division of Rheumatology, Johns Hopkins University, Baltimore, MD, USA

5Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA 94305, USA


Systemic Sclerosis 2011

Description

Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by widespread fibrosis affecting the skin, internal organs, and vasculature. Yet, most available therapies for SSc are organ-specific, such as proton pump inhibitors for gastroesophageal reflux; angiotensin converting enzyme inhibitors for renal crisis; several vasodilating therapies such as phosphodiesterase-5 inhibitors, endothelin receptor antagonists, and prostacyclin analogues for pulmonary arterial hypertension. However, there are currently no systemic, disease modifying therapies available for the treatment of this condition and the outcomes remain poor.

We invite authors to submit original research articles, review articles, or case reports describing emerging therapies for SSc. Manuscripts may focus on any form of therapy for SSc including nonmedical therapies, such as physical therapy or complementary medicine approaches; medications targeting specific organs/symptoms; disease modifying therapies; immunomodulatory treatments; antifibrotic agents; or biologic therapies. Manuscripts can describe preclinical, clinical, or translational studies related to new therapies for SSc. Potential topics include, but are not limited to:

  • Preclinical evaluation of novel therapies in animal models of SSc
  • Early and late phase clinical trial safety and/or efficacy results
  • Translational studies identifying novel therapeutic targets for SSc
  • Case reports or case series of SSc patients treated with available biologic or immunomodulatory agents

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijr/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2011
  • - Article ID 308231
  • - Editorial

Systemic Sclerosis 2011

Lorinda Chung | Oliver Distler | ... | Virginia Steen
  • Special Issue
  • - Volume 2011
  • - Article ID 976427
  • - Review Article

Primary Biliary Cirrhosis Associated with Systemic Sclerosis: Diagnostic and Clinical Challenges

Cristina Rigamonti | Dimitrios P. Bogdanos | ... | Andrew K. Burroughs
  • Special Issue
  • - Volume 2011
  • - Article ID 824972
  • - Review Article

A System Out of Breath: How Hypoxia Possibly Contributes to the Pathogenesis of Systemic Sclerosis

T. W. van Hal | L. van Bon | T. R. D. J. Radstake
  • Special Issue
  • - Volume 2011
  • - Article ID 829751
  • - Review Article

The Role of Intravenous Immunoglobulin Preparations in the Treatment of Systemic Sclerosis

Marta Baleva | Krasimir Nikolov
  • Special Issue
  • - Volume 2011
  • - Article ID 305238
  • - Review Article

Gastric Antral Vascular Ectasia in Systemic Sclerosis

Jill Johnson | Chris T. Derk
  • Special Issue
  • - Volume 2011
  • - Article ID 392542
  • - Review Article

PDE-5 Inhibitors in Scleroderma Raynaud Phenomenon and Digital Ulcers: Current Status of Clinical Trials

Ann J. Impens | Kristine Phillips | Elena Schiopu
  • Special Issue
  • - Volume 2011
  • - Article ID 275617
  • - Research Article

Basal Activation of Type I Interferons (Alpha2 and Beta) and OAS Genes: Insights into Differential Expression Profiles of Interferon System Components in Systemic Sclerosis

Danilo Bretas de Oliveira | Gabriel Magno de Freitas Almeida | ... | Erna Geessien Kroon
  • Special Issue
  • - Volume 2011
  • - Article ID 201787
  • - Review Article

Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis

Kait Arefiev | David F. Fiorentino | Lorinda Chung
  • Special Issue
  • - Volume 2011
  • - Article ID 270938
  • - Review Article

Vascular Changes in Bleomycin-Induced Scleroderma

Toshiyuki Yamamoto | Ichiro Katayama
  • Special Issue
  • - Volume 2011
  • - Article ID 208219
  • - Review Article

Blocking TGFβ via Inhibition of the αvβ6 Integrin: A Possible Therapy for Systemic Sclerosis Interstitial Lung Disease

Tamiko R. Katsumoto | Shelia M. Violette | Dean Sheppard
International Journal of Rheumatology
 Journal metrics
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Acceptance rate7%
Submission to final decision73 days
Acceptance to publication23 days
CiteScore3.700
Journal Citation Indicator0.460
Impact Factor2.3
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