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International Journal of Reproductive Medicine
Volume 2014, Article ID 257974, 5 pages
http://dx.doi.org/10.1155/2014/257974
Clinical Study

Body Mass Index and Pregnancy Outcome after Assisted Reproduction Treatment

1Department of Public Health and Community Medicine, Faculty of Medicine, Al-Azhar University, Nasr City, Cairo, Egypt
2Assisted Reproductive Technology (ART) Unit, International Islamic Centre for Population Studies and Research (IICPSR), Al-Azhar University, Cairo, Egypt

Received 23 December 2013; Accepted 31 January 2014; Published 5 March 2014

Academic Editor: Hind A. Beydoun

Copyright © 2014 Khaled Kasim and Ahmed Roshdy. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The present study aimed to evaluate the impact of body mass index (BMI) on pregnancy outcome after intracytoplasmic sperm injection (ICSI). The study analyzed pregnancy outcome of 349 women who underwent ICSI by their BMI: <25, 25–<30, and ≥30 kg/m2. The associations were generated by applying logistic regression models. A significant reduction in positive pregnancy outcome was observed among overweight and obese women (odds ratio (OR) = 0.50; 95% confidence interval (CI) = 0.25–0.99 for overweight women and OR = 0.45; 95% CI = 0.20–0.89 for obese women). These estimates show that the pregnancy rates are reduced with increasing BMI. The effect of obesity on pregnancy outcome was absent when three and more embryos were transferred. Our study contributes to the reports linking overweight and obesity with decreased positive pregnancy outcome after ICSI and suggests women’s age, infertility type, and number of embryos transferred to modify this reducing effect.