Clinical Study
Could Metformin Manage Gestational Diabetes Mellitus instead of Insulin?
Table 5
Neonatal outcomes.
(a) |
| Variable | Metformin | Insulin | value | : 67 | : 70 | % | | % | |
| Hypoglycemia | 10.4% | 7 | 21.4% | 15 | 0.01 | Transient tachypnea | 2.9% | 2 | 4.2% | 3 | 0.67 | Respiratory distress | 1.4% | 1 | 2.8% | 2 | 0.85 | Neonatal jaundice | 19.4% | 14 | 15.7% | 11 | 0.31 | Phototherapy | 19.4% | 14 | 15.7% | 11 | 0.31 | Neonatal intensive care unit admission | 14.9% | 10 | 17.1% | 12 | 0.51 | Birth trauma | 0% | 0% | |
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(b) |
| Variable | Metformin | Insulin | value | : 67 | : 70 | % | | % | |
| Apgar score at 5 minutes < 7 | 1.5% | 1 | 1.4% | 1 | 0.59 | Gestational age at birth | 38.7 ± 1.1 | 38.9 ± 1.4 | 0.06 | Estimated weight > 90th percentile | 14.9% | 10 | 15.7% | 11 | 0.89 | Estimated weight < 10th percentile | 5.9% | 4 | 7.1% | 5 | 0.31 | Congenital anomalies | 1.5% | 1 | 2.8% | 2 | 0.91 |
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