Determining the Optimal Duration of Progesterone Supplementation prior to Transfer of Cryopreserved Embryos and Its Impact on Implantation and Pregnancy Rates: A Pilot Study

Table 2

Some studies dealing with estrogen/progesterone supplementation to prepare endometrium before transfer of cryopreserved-thawed embryos.

Reference	Transfer of the following:	Estrogen preparation by the following:	Progesterone preparation by the following:	Days of progesterone exposure
Muasher et al., 1991 [9]	Day 2 embryos	Estradiol patches	Intramuscular progesterone	3
Pattinson et al., 1992 [10]	Day 2 embryos	Estradiol	Vaginal progesterone	3
Pattinson et al., 1994 [11]	Day 2 embryos	Estradiol	Vaginal progesterone	3
Lelaidier et al., 1995 [12]	Blastocysts	Estradiol	Vaginal progesterone	5
Queenan et al., 1997 [13]	Day 2 embryos	Estradiol patches	Intramuscular progesterone	3
Queenan et al., 1997 [14]	Day 2 embryos	Estradiol patches	Intramuscular progesterone	3
Horne et al., 1997 [15]	Day 2 embryos	Estradiol valerate	Vaginal progesterone	4
Simon et al., 1998 [16]	Day 2-3 embryos	Estradiol	Vaginal progesterone	2-3
Simon et al., 1999 [17]	Day 2-3 embryos	Estradiol	Vaginal progesterone	2-3
Banz et al., 2002 [18]	Day 2 embryos	Estradiol patches	Vaginal progesterone	3
Seelig et al., 2002 [19]	Day 2 embryos	Estradiol valerate	Vaginal progesterone	3
Schröder et al., 2003 [20]	Day 2 embryos	Estradiol patches	Vaginal progesterone	3
Dal Prato et al., 2002 [21]	Day 2 embryos	Estradiol patches	Intramuscular progesterone	3
Boldt et al., 2003 [22]	Day 3 embryos	Estradiol	Intramuscular progesterone	3
Revel et al., 2004 [23]	Day 3 embryos	Estradiol	Vaginal progesterone	3

Source: Nawroth and Ludwig [6].