Outcome in Advanced Ovarian Cancer following an Appropriate and Comprehensive Effort at Upfront Cytoreduction: A Twenty-Year Experience in a Single Cancer Institute

Table 2

Predictive factors of survival.

Predictive factors	Number of patients	Overall survival		Disease-free survival
		5-year survival (%)	𝑃	5-year survival (%)	𝑃
Age
<60 years	180	36.1	𝑃=.002	27.7	𝑃=.68
≥60 years	160	26.1		26.9
Menopausal status
No	95	43.7	𝑃=.001	31.5	𝑃=.128
Yes	237	36.4		25.4
Residual disease after surgery
<1 cm (without  residual disease)	135 (69)	43.5 (55.4)	𝑃=.0002	27.6 (40.6)	𝑃=.58
≥1 cm	204	24.2		26.7
Lymph node dissection (picking)
No	279	29	𝑃=.02	24.8	𝑃=.01
Yes	61	42.5		37.8
FIGO stage
III	264	34.6	𝑃=.002	25.7	𝑃=.15
IV	76	19.1		33.6
Histology
Serous	277	31.2		26.3
Mucinous	9	22.2	𝑃=.005	48.6	𝑃=.0007
Endometrioid	26	45.0		42.9
Clear cell	4	25.0		25.0
Undifferentiated	12	38.9		—
Other	12	8.3		—
Grade (2 classes)
1	13	58.6	𝑃=.005	60.0	𝑃=.05
2 and 3	140	24.8		16.0
Chemotherapy
Platinum and   alkylating agents	217	30.3	𝑃=.107	38.2	𝑃=.02
Platinum and   Paclitaxel	116	34.6		26.7

NS = not significant.