Clinical Study
Transcatheter Arterial Chemoembolization Is a Feasible Palliative Locoregional Therapy for Breast Cancer Liver Metastases
Table 2
Details of TACE treatments and tumor response of breast cancer patients with hepatic metastases.
| Patient | Chemothe-rapeutic Agent | Dose of chemotherapy used in each cycle () | Number of TACE cycles | Interval between first TACE and death/last F/U (in month) | Interval between diagnosis of liver metastasis and death/last F/U (in month) | Radiological response after third TACE | Radiological response after last TACE | Tumor marker response | New extrahepatic metastasis during TACE | Morbidity of TACE |
| 1 | adriamycin | 80 | 3 | 6 | 12 | progression | progression | CA125-increase | new left axillary LN | neutropenia |
| 2 | cisplatin Gemcitabine | 125/1250 | 3 | 7 | 64 | progression | progression | CA125-increase CA153-increase | new pulmonary metastasis | none |
| 3 | oxaliplatin | 85 | 1 | 1 | 1 | N/A | progression | CA153-increase CA125-decrease | none | nausea & vomiting |
| 4 | cisplatin | 165 | 5 | 12 | 19 | progression | progression | CA125-increase CA153-increase | new bony metastasis | nausea & vomiting |
| 5 | adriamycin | 40 | 5 | 16 | 42 | stable disease | partial response | CEA-decrease CA153-decrease | new bony metatasis | nausea, neutropenia |
| 6 | adriamycin | 5060 | 5 | 16 | 65 | progression | progression | CA153-decrease | none | nausea, abdo pain neutropenia, anemia |
| 7 | cisplatin gemcitabine | 150/1500 | 3 | 24 | 24 | partial response | partial response | CA153-decrease | none | nausea |
| 8 | adriamycin | 50 | 3 | 8 | 28 | progression | progression | CA153-increase | none | abdo pain |
| 9 | adriamycin | 50 | 4 | 9 | 9 | stable disease | stable disease | CA153-decrease | new bony metastasis | abdo pain |
| 10 | adriamycin | 40 | 10 | 26 | 39 | stable disease | stable disease | CA153-decrease | new bony metastasis | none |
|
|