Clinical Study

Gastrointestinal Complications in 147 Consecutive Patients with Peritoneal Surface Malignancy Treated by Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy

Table 1

Patients characteristics, quantitative prognosis indicators, peritonectomies, visceral resections, and intraoperative treatments.

Variablen

Total Patients147
 Gender
 Male68 (46%)
 Female79 (54%)
Age at the time of surgery (years)
 Mean ± 1 Standard Deviation49.9 (±8.7)
 Median51
 Range23–64
Primary cancer diagnosis
 Appendiceal cancer135 (92%)
 Colorectal cancer12 (8%)
Histological grade
 Grade 161 (41.6%)
 Grade 212 (8%)
 Grade 374 (50.4%)
Prior surgical score
 0–2133 (90.5%)
 314 (9.5%)
Peritoneal cancer index
 0–1031 (21%)
 11–2040 (27%)
 21–3053 (36%)
 31–3923 (16%)
Completeness of cytoreduction
 Complete125 (85%)
 Incomplete22 (15%)
Peritonectomy procedures
 Pelvic123 (84%)
 Right upper quadrant109 (74%)
 Left upper quadrant72 (49%)
 Omental bursa70 (48%)
 Anterior abdominal wall50 (34%)
Peritonectomy procedures per patient
 zero18 (12%)
 one21 (14%)
 two16 (11%)
 three29 (20%)
 four31 (21%)
 five32 (22%)
Visceral resections performed
 Greater omentectomy144 (98%)
 Splenectomy84 (57%)
 Rectosigmoid colon resection70 (48%)
 Right colon resection57 (39%)
 Hysterectomy47 (32%)
 Small bowel resection29 (20%)
 Transverse colon resection20 (14%)
 Gastrectomy4 (3%)
Visceral resections per patient
 Zero2 (1.4%)
 One20 (13.6%)
 Two34 (23.1%)
 Three34 (23.1%)
 Four32 (21.8%)
 Five15 (10.2%)
 Six8 (5.4%)
 Seven2 (1.4%)
Anastomoses performed
 Esophageal2 (1.4%)
 Small bowel22 (15.0%)
 Ileocolic29 (19.7%)
 Colocolic3 (2.0%)
 Colorectal56 (38.1%)
Anastomoses performed per patient
 Zero74 (50.3%)
 One44 (29.9%)
 Two21 (14.3%)
 Three6 (4.1%)
 Four2 (1.4%)
Ostomies performed
 Diverting ileostomy30 (20.4%)
 End ileostomy13 (8.8%)
 None67 (70.8%)
Blood replacement
 None39 (26.5%)
 Blood 1–368 (46.3%)
 Blood 4–635 (23.8%)
 Blood > 65 (3.4%)
Fresh frozen plasma replacement
 None80 (54.4%)
 Plasma 1–451 (34.7%)
 Plasma >416 (10.9%)
Time in operating room (hours)
 0–610 (6.89%)
 6–12124 (84.4%)
 > 1213 (8.8%)
Chemotherapy treatments
 HIPEC only82 (55.8%)
 HIPEC plus EPIC65 (44.2%)