Clinical Study

Gastrointestinal Complications in 147 Consecutive Patients with Peritoneal Surface Malignancy Treated by Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy

Table 2

The total number of gastrointestinal adverse events grade I through grade IV.

Organ SystemGrade I-Asymptomatic and self-limitingGrade II-Symptomatic and medical treatmentGrade III-Invasive interventionGrade IV-ICU care or return to operating room
Gastrointestinal System

Anastomotic failureSub-clinical, afebrile, radiologic diagnosis (0)Antibiotics, febrile (0)Percutaneous drainage (0)Reoperation (3)
FistulaSub-clinical, afebrile, radiologic diagnosis (0)Antibiotics, febrile (0)Percutaneous drainage (0)Reoperation (3)
Pancreatic fistulaElevated enzymes in drains (0)TPN and somatostatin (0)Percutaneous drainage (0)Reoperation (1)
PancreatitisElevated enzymes (4)≤3 Ranson’s score (4)4–6 Ranson’s score (0)Reoperation/ICU (1)
Bile leakBile only in drain (0)Bile in drain, febrile (2)Percutaneous drainage (0)Reoperation (1)
Chyle leakTransient (1)Prolonged 1 week (0)Cease prior to discharge (0)Persist past hospital discharge (0)
Prolonged ileusN/G (0)N/G > 2 weeks (1)N/G >3 weeks (0)Persist past hospital discharge (0)
Small bowel obstructionAbdominal pain (0)Abdominal pain, N/G reinsertion (0)Repeat radiologic studies (0)Reoperation (1)
Nausea/vomitingTransient vomiting (0)Vomiting, anti-emetics (7)Vomiting, IV therapy (4)Vomiting with surgical intervention or ICU (1)
DiarrheaTransient <2 days (0)Tolerable, but >2 days (1)Intolerable, IV therapy (0)Dehydration prolonged IV therapy (0)
AscitesMild (0)Fluid restriction (0)Symptomatic, percutaneous tap (0)Compromising vital function, ICU care (0)