International Journal of Surgical Oncology / 2011 / Article / Tab 3 / Clinical Study
Gastrointestinal Complications in 147 Consecutive Patients with Peritoneal Surface Malignancy Treated by Cytoreductive Surgery and Perioperative Intraperitoneal Chemotherapy Table 3 Univariate and multivariate analysis (gastrointestinal events).
Gastrointestinal events I–IV univariate analysis Gastrointestinal events I–IV multivariate analysis Yes
No
Value*/OR Odds Ratio
Value
Gender Male 12 56 0.8480
NT** Female 13 66 0.9 (
)
Age ≤50 year 14 58 0.4408
NT >50 year 11 64 0.7 (
)
Location Appendix 22 113 0.4297
NT Colorectal 3 9 1.7 (
)
Grade Grade 1 5 56 0.0166
0.1345 Grades 2-3 20 66 0.3 (
)
Prior Surgical Score 0–2 23 110 1.0000
NT 3–5 2 12 0.8 (
)
Peritoneal Cancer Index (4 groups) 0–10 3 28 Reference
NT 11–20 6 34 0.7220
) 21–30 7 46 0.7384
) 31–39 9 14 0.0100
)
Peritoneal Cancer Index (2 groups B) 0–30 16 108 0.0049
2.8 (0.9,8.4)
0.0586 31+ 9 14 4.3 (
)
Completeness of Cytoreduction Complete 18 107 0.0625
NT Incomplete 7 15 2.8 (
)
Peritonectomy Procedure Pelvic 21 102 1.0000
) NT Right Upper Quardrant 19 90 0.8166
) NT Left Upper Quardrant 11 61 0.5846
) NT Omental Bursa 12 58 0.9666
) NT Anterior Abdominal Wall 11 39 0.2473
) NT
Peritonectomy Procedure per patient 0–2 8 47 0.5391
NT 3–5 17 75 1.3 (
)
Visceral Resections Performed Omentectomy 24 120 0.4308
) NT Splenectomy 15 69 0.7513
) NT Rectosigmoid colon 14 43 0.0524
) NT Right colon resection 15 55 0.1736
) NT Hysterectomy 4 43 0.0601
) NT Small bowel resection 9 20 0.0493
) 1.3 (
) 0.6202 Transverse colon 5 15 0.3377
) NT Gastrectomy 2 2 0.1343
) NT
Visceral Resections Performed per patient 0–2 7 49 0.2539 NT 3–7 18 73 1.7 (
)
Anastomoses performed Esophago-jejunal 1 1 0.3122
) NT Small bowel 7 15 0.0605
) NT Ileocolic 7 22 0.2741
) NT Colocolic 1 2 0.4308
) NT Colorectal 14 42 0.0430
) 1.4 (
) 0.4986
Anastomoses performed per patient 0–2 21 118 0.0288
1.9 (
)
0.4616 3–5 4 4 5.6 (
)
Ostomies performed None 15 89 reference Diverting ileostomy 8 22 0.1172
) NT End ileostomy 2 11 1.0000
) NT
Blood replacement None 7 32 reference Blood 1–3 8 60 0.3752
) NT Blood 4–6 9 26 0.4178
) NT Blood > 6 1 4 1.0000
) NT
Fresh frozen plasma replacement None 13 67 reference Plasma 1–4 7 44 0.6953
) NT Plasma > 4 5 11 0.1724
) NT
Time in operating room (hours) 0–6 2 8 reference 7–12 18 106 0.6445
) NT >12 5 8 0.450
) NT
Chemotherapy treatment HIPEC only 10 69 0.2314
NT HIPEC plus EPIC 13 52 1.7 (
) Unknown 2 1
*: Pearson Chi-square, or Fisher's exact test if sparse distribution. **: NT means Not Tested in multivariate modeling due to non significant univariate test.
