Clinical Study

Yttrium-90 Radioembolization for Colorectal Cancer Liver Metastases: A Single Institution Experience

Table 2

Treatment characteristics: Floxuridine (FUDR) was given with 90Y in some of our earlier patients. FUDR (5 mg/kg) was given just prior to administration of the 90Y microspheres.

n (%)MedianRange

Total number of treatments90
Patients with 1 treatment20 (39.2)
Patients with 2 treatments27 (52.9)
Patients with 4 treatments4 (7.8)
Radiation dose to target tissue per treatment (Gy)44.412.9–67.2
Radiation activity per treatment (GBq)0.890.16–2.20
FUDR with 90Y*
 Yes17 (33.3)
 No34 (66.7)
Lung shunt (%)3.30.4–11.5
Treatments terminated early due to embolic process40 (44.4)
Treatments with ≥80% of prescribed dose administered67 (74.4)

*Those who had prior hepatic artery chemoinfusion separate from the time of 90Y administration are not included in this group.