Lymphadenectomy in Management of Invasive Bladder Cancer

Table 5

Cut-off lymph node densities and their effect upon oncological outcomes.

References	Year	No. of patients	Median number of LNs removed (range)	Cut-off PLND	5-Y survival rates
					Below cut-off	Above cut-off
Stein et al. [41]	2003	244	30 (1–96)	20	17	44
Herr [42]	2003	162	13 (2–32)	20	8*	64*
Kassouf et al. [43]	2006	108	12 (1–58)	25	11	38
Kassouf et al. [44]	2008	248	12 (2–58)	20	15*	55*
Fleischmann et al. [45]	2005	101	22 (10–43)	20	15	41
Steven and Poulsen [24]	2007	64	27 (11–49)	20	25	47
Abdel–Latif et al. [11]	2004	110	18 (mean)	20	16	39
Wiesner et al. [54]	2009	152	33 (15–77)	11	8*	34*
Osawa et al. [27]	2009	435	12 (1–80)	25	12*	51*

All studies reported RFS except *reported CSS.